The Quahada band of Comanches, fiercest of all bands, was under his leadership. Quanah led Cheyennes, Arapahoes, Comanches, Kiowas and Apaches in their last great surge against white encroachment - known as Battle of Adobe Walls. A military strategist of the first order, he became one of the most feared Indians on the Southern Plains. But the white man was superior in weapons and numbers. The day came when Quanah knew that further resistance would lead only to the annihilation of the Comanches. He counseled his people to lay down their arms and “take the white man’s road.” On June 2, 1875, Quanah and his followers surrendered at Fort Sill. By an ironic twist of fate, it was Quanah who led the Comanches in their final struggle against white encroachment - his mother’s own people - and once again the fighting was over, it was he - as last Chief of the Comanches - who was to lead them up from the bitter ashes of defeat to walk “the white man’s road.” Quanah dedicated himself to the strenuous task of guiding the Comanches into civilization.
Courageous and strong-willed, he was also a natural diplomat. Traveling numerous times to Washington D.C. to represent the Comanches, he became a familiar figure in Congress. He became a successful farmer and rancher and became a major stockholder in the Quanah, Acme and Pacific Railway. His beautiful two story home, complete with veranda and star emblazoned roof, was built at the foothills of the Wichita Mountains. He had vital interest in educating the young and became president of his local school board. He was appointed presiding judge in the Court of Indian Offenses and numbered statesmen and ambassadors among his friends. In 1905 Quanah rode in Theodore Roosevelt’s inaugural parade. In a special report to the President, it was stated of Quanah “If ever Nature stamped a man with the seal of headship, she did it in his case. Quanah would have been a leader and a governor in any circle where fate may have cast him.”